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DeCS
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Descriptor English:
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Helix-Turn-Helix Motifs
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Descriptor Spanish:
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Secuencias Hélice-Giro-Hélice
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Descriptor Portuguese:
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Sequências Hélice-Volta-Hélice
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Synonyms English:
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HTH Motif
HTH Motifs
Helix Turn Helix Motifs
Helix-Turn-Helix Motif
Motif, HTH
Motif, Helix-Turn-Helix
Motifs, HTH
Motifs, Helix Turn Helix
Motifs, Helix-Turn-Helix
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Tree Number:
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G02.111.570.820.709.275.500.360.360
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Definition English:
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The first DNA-binding protein motif to be recognized. Helix-turn-helix motifs were originally identified in bacterial proteins but have since been found in hundreds of DNA-BINDING PROTEINS from both eukaryotes and prokaryotes. They are constructed from two alpha helices connected by a short extended chain of amino acids, which constitute the "turn." The two helices are held at a fixed angle, primarily through interactions between the two helices. (From Alberts et al., Molecular Biology of the Cell, 3d ed, p408-9) |
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Indexing Annotation English:
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do not confuse with HELIX-LOOP-HELIX MOTIFS
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History Note English:
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96; was see HELIX-LOOP-HELIX MOTIFS 1994-95
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Allowable Qualifiers English:
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Record Number:
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32734
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Unique Identifier:
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D019077
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Occurrence in VHL:
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Similar:
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DeCS
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